Key result
Tricuspid TEER yields clinical improvement with 0 complications in heart transplant recipients with severe TR.
Why the study?
Tricuspid regurgitation in orthotopic heart transplantation recipients is common and linked to poor outcomes, but surgical intervention carries high risk.
Does tricuspid transcatheter edge-to-edge repair improve outcomes in orthotopic heart transplantation recipients with severe symptomatic tricuspid regurgitation?
Case Report (n=4)
Does tricuspid transcatheter edge-to-edge repair improve outcomes in orthotopic heart transplantation recipients with severe symptomatic tricuspid regurgitation?
Tricuspid transcatheter edge-to-edge repair may be a safe and effective treatment option for severe symptomatic tricuspid regurgitation in orthotopic heart transplant recipients.
May support feasibility in transplant recipients; leaves open need for larger prospective trials before practice change.
Tricuspid regurgitation in orthotopic heart transplantation recipients is a common complication that has been associated with poor outcomes. Surgical intervention carries a high risk in this population given prior sternotomy, immunosuppression, and comorbidities. We report a case series of 4 orthotopic heart transplantation recipients with severe symptomatic tricuspid regurgitation who were treated successfully with tricuspid transcatheter edge-to-edge repair. All patients demonstrated clinical and echocardiographic improvement postprocedure, with no procedural complications or rehospitalizations at short-term follow-up.
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Kharsa et al. (2026) conducted a case report in Severe symptomatic tricuspid regurgitation in orthotopic heart transplantation recipients (n=4). Tricuspid transcatheter edge-to-edge repair was evaluated on Clinical and echocardiographic improvement, procedural complications, and rehospitalizations. Tricuspid transcatheter edge-to-edge repair in 4 heart transplant recipients with severe tricuspid regurgitation resulted in clinical improvement with 0 procedural complications or rehospitalizations.
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