Key result
Dromedary camels were completely resistant to FMDV type A infection, whereas Bactrian camels developed moderate to severe clinical signs of FMD, viraemia, and high antibody titres.
Why the study?
Are dromedary and Bactrian camels susceptible to foot-and-mouth disease virus (FMDV) type A infection?
Population
21 animals: 8 dromedary camels, 2 Bactrian camels, and 2 sheep inoculated with FMDV type A SAU 22/92; plus 5…
Comparison
Inoculation with 10^7.0 TCID50 of foot-and-mouth… vs Inoculated sheep and uninoculated contact animals.
Design
Preclinical
Follow-up
up to 130 days post-inoculation
Authors
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Highlights species-specific FMDV risks among camels for targeted monitoring; leaves open mechanisms of dromedary resistance.
Are dromedary and Bactrian camels susceptible to foot-and-mouth disease virus (FMDV) type A infection?
Bactrian camels are susceptible to FMDV infection and develop clinical disease, whereas dromedary camels are resistant, indicating species-specific differences in FMDV susceptibility among camelids.
Larska et al. (2008) studied Foot-and-mouth disease (n=21). FMDV type A SAU 22/92 inoculation vs. Dromedary camels vs Bactrian camels vs Sheep was evaluated on Susceptibility to FMDV (clinical signs, viraemia, and seroconversion). Dromedary camels were completely resistant to FMDV type A infection, whereas Bactrian camels developed moderate to severe clinical signs of FMD, viraemia, and high antibody titres.
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