Key result
Type I diabetes was not associated with impaired forearm vasodilatory capacity compared to healthy controls in the absence of other cardiovascular risk factors.
Why the study?
Does Type I diabetes impair forearm vasoreactivity compared to healthy controls in the absence of other cardiovascular risk factors?
Case-Control (n=30)
Does Type I diabetes impair forearm vasoreactivity compared to healthy controls in the absence of other cardiovascular risk factors?
Type I diabetes does not appear to impair forearm vasodilatory capacity in the absence of other cardiovascular risk factors.
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Uncomplicated T1D may not impair forearm vasodilatory capacity; hypothesis-generating and leaves open whether comorbidities are required for endothelial dysfunction.
Allen et al. (2001) conducted a case-control in Type I Diabetes (n=30). Type I Diabetes vs. Healthy controls was evaluated on Forearm blood flow at rest, after arterial occlusion, and following occlusion with handgrip exercise. Type I diabetes was not associated with impaired forearm vasodilatory capacity compared to healthy controls in the absence of other cardiovascular risk factors.
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