CBDMB rapidly inhibits sarcolemmal Na+/Ca2+ exchange in rat ventricular cardiomyocytes, but with longer preincubation, it inhibits L-type Ca2+ channels with even higher potency.
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CBDMB's ion channel effects in rat cells warrant no clinical extrapolation; leaves open selective NCX inhibition as a research tool pending higher-order validation.
Sharikabad et al. (1997) studied this question.
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