Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 4, 2017GenomicsOpen Access

Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways

View Full Paper
Ask AI
Bookmark
Share

Key result

Integration of available literature enabled the construction of a regulatory pathway for ANGPTL8 on WikiPathways to visualize its role in glucose and lipid metabolism.

Design

Other

Authors

ASAmnah SiddiqaCincinnati Children's Hospital Medical CenterECElisa CirilloThe Hyve (Netherlands)STSamar TareenBabraham Institute

Discussion

Loading...

Member takes

Implication

Provides a WikiPathways resource for ANGPTL8 omics research; leaves open validation before any clinical use in diabetes or dyslipidemia.

PICO

P
Population
Diabetes mellitus and dyslipidemia
I
Intervention / Comparator
ANGPTL8
O
Primary Outcome
Construction of a regulatory pathway

This study provides an integrated pathway view of ANGPTL8's regulation, serving as a resource for future omics-based studies in diabetes and dyslipidemia.

Cite This Study

Siddiqa et al. (2017) studied Diabetes mellitus and dyslipidemia. ANGPTL8 was evaluated on Construction of a regulatory pathway. Integration of available literature enabled the construction of a regulatory pathway for ANGPTL8 on WikiPathways to visualize its role in glucose and lipid metabolism.

synapsesocial.com/papers/6a98d4a23ea09d5cf8f59936https://doi.org/10.1016/j.ygeno.2017.06.006
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking2016 · 227 citations
  2. 2A dual role of lipasin (betatrophin) in lipid metabolism and glucose homeostasis: consensus and controversy2014 · 113 citations
  3. 3Thyroid Hormone Regulation of Metabolism2014 · 2,454 citations
  4. 4Chromosome 19 open reading frame 80 is upregulated by thyroid hormone and modulates autophagy and lipid metabolism2013 · 80 citations
  5. 5MicroRNA hsa-miR-613 Targets the Human LXRα Gene and Mediates a Feedback Loop of LXRα Autoregulation2011 · 78 citations