Population
Single atrial myocytes of guinea pig heart
Comparison
Glibenclamide vs Control conditions (absence of glibenclamide)
Design
Preclinical
Authors
Loading...
Supports selective KATP blockade by glibenclamide in guinea pig atrial myocytes; leaves open translation to human electrophysiology.
Glibenclamide specifically and concentration-dependently inhibits ATP-sensitive K+ channel currents in guinea pig atrial myocytes without affecting other K+ currents.
Hamada et al. (1990) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: