Why the study?
Does single- and double-balloon valvuloplasty increase valvular area and cause morphological changes in excised fibrotic and calcific mitral valves?
Population
15 excised fibrotic and calcific mitral valves from patients undergoing mitral valve replacement
Comparison
Single-balloon valvuloplasty followed by… vs Pre-expansion baseline
Design
Preclinical
Authors
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Double-balloon dilatation may increase mitral valve area more than single-balloon in fibrotic valves; leaves open in vivo safety and efficacy.
Does single- and double-balloon valvuloplasty increase valvular area and cause morphological changes in excised fibrotic and calcific mitral valves?
Double-balloon valvuloplasty provides greater expansion of fibrotic and calcific mitral valves compared to single-balloon, primarily via commissural splitting, but carries a risk of leaflet rupture.
Reifart et al. (1990) studied this question.
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