Why the study?
Does perindopril restore the lower limit of cerebral blood flow autoregulation in renovascular hypertensive rats?
Does perindopril restore the lower limit of cerebral blood flow autoregulation in renovascular hypertensive rats?
Chronic ACE inhibition with perindopril normalizes blood pressure and restores the lower limit of cerebral blood flow autoregulation in a rat model of renovascular hypertension.
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Perindopril effects in renovascular hypertensive rats are hypothesis-generating; leaves open translation to human cerebral autoregulation.
Muller et al. (1990) studied this question.
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