Key result
A 52-year-old male was diagnosed with acute thrombosis of the intramuscular gastrocnemius vein despite presenting with a normal D-dimer level of 320 mg/L.
Why the study?
Although D-dimer testing typically has high sensitivity for ruling out acute VTE, multiple factors can alter its sensitivity and specificity.
Population
A 52-year-old male patient with deep venous thrombosis
Design
Case report
Authors
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Factors like cancer and inflammation may alter D-dimer accuracy after craniotomy; leaves open optimal VTE screening thresholds.
Case Report (n=1)
This case highlights that acute deep venous thrombosis can occur even in the presence of a normal D-dimer level, emphasizing the need for clinical judgment and imaging when suspicion is high.
Zaki et al. (2021) conducted a case report in Deep venous thrombosis (DVT) (n=1). Normal D-dimer level was evaluated on Presence of deep venous thrombosis on Doppler ultrasound. A 52-year-old male was diagnosed with acute thrombosis of the intramuscular gastrocnemius vein despite presenting with a normal D-dimer level of 320 mg/L.
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