This case report highlights the potential risks of peripartum anticoagulation in pregnant women with Eisenmenger's syndrome, suggesting it may contribute to fatal outcomes rather than preventing them.
May warrant caution with peripartum anticoagulation in Eisenmenger syndrome; leaves open optimal management strategies pending further data.
To the Editor: Eisenmenger's syndrome consists of pulmonary hypertension with a reversed or bidirectional shunt at the atrial, ventricular, or aortopulmonary level1. Pregnancy should ideally be avoided in a woman with Eisenmenger's syndrome, since it carries a high (approximately 50 percent) risk of sudden death, frequently occurring a few days postpartum2. Because pulmonary thromboembolism may be a cause of sudden death in this setting,3,4 anticoagulation in the peripartum period has been suggested as a method to lower this risk,3 but it may instead contribute to a fatal outcome. A 32-year-old woman was transferred to our hospital. At . . .
No takes yet. Share an insight, caveat, or question.
Mark L. Kahn (1993) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: