November 1, 1976Applied and Environmental MicrobiologyOpen Access

Concentration and purification of enteroviruses by membrane chromatography

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Population

Enteroviruses from tissue culture harvests

Design

Preclinical

Authors

MHMarilyn HendersonBaylor College of Medicine CWCraig WallisUniversity of Worcester JMJ. L. MelnickBaylor College of Medicine

Discussion

Member takes

Implication

May improve lab-based virus purification efficiency; leaves open clinical translation pending human validation.

Structured PICO

Population

Enteroviruses from tissue culture harvests

Intervention

Membrane chromatography procedure involving cationic detergent, cationic-exchange resin, acidification, adsorption to epoxy-fiberglass membranes, and elution with pH 11.5 glycine-NaOH buffer

Outcome

Concentration and purification efficiencysurrogate

The described membrane chromatography procedure allows for up to 500-fold concentration and purification of enteroviruses from tissue culture harvests.

Cite This Study

Henderson et al. (1976) studied this question.

synapsesocial.com/papers/6a98df474129c1a0f6748ed3 https://doi.org/10.1128/aem.32.5.689-693.1976

View Full Paper

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Bookmark

Concentration and purification of enteroviruses by membrane chromatography

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Concentration and purification of enteroviruses by membrane chromatography

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider