Why the study?
Does carbon tetrachloride-induced acute renal failure alter angiotensin I-converting enzyme activity in rats?
Population
Rats with carbon tetrachloride (CCl4)-induced acute renal failure
Design
Preclinical
Follow-up
7 days
Authors
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May mark proximal tubule damage in rat ARF models; leaves open biomarker utility in human AKI.
Does carbon tetrachloride-induced acute renal failure alter angiotensin I-converting enzyme activity in rats?
Increased urine ACE activity may serve as an indicator of proximal tubule damage in acute renal failure.
Pedraza‐Chaverrí et al. (1993) studied this question.
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