Why the study?
Do TNF-alpha and IL-6 levels in ascitic fluid differentiate between spontaneous bacterial peritonitis and sterile ascites in alcoholic cirrhotic patients?
Population
30 alcoholic cirrhotic patients
Comparison
Measurement of TNF-alpha, IL-1, and IL-6 in… vs Patients with sterile ascitic fluid
Design
Cohort
Follow-up
48 hours (for antibiotic treatment monitoring)
Authors
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May aid SBP differentiation in cirrhosis; hypothesis-generating and requires prospective validation before clinical use.
Do TNF-alpha and IL-6 levels in ascitic fluid differentiate between spontaneous bacterial peritonitis and sterile ascites in alcoholic cirrhotic patients?
TNF-alpha and IL-6 in ascitic fluid are significantly elevated in spontaneous bacterial peritonitis and may serve as diagnostic and treatment monitoring markers.
Zéni et al. (1993) studied this question.
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