Why the study?
Does static lung inflation reflexly depress cardiovascular function in a dog model?
Population
Dogs with isolated left airway and left pulmonary artery
Comparison
Static inflations of the left lung to 30 cmH2O vs Baseline state and state after transection of…
Design
Preclinical
Authors
Loading...
Lung inflation elicits vagally mediated cardiovascular depression in dogs; hypothesis-generating for human cardiopulmonary reflexes.
Does static lung inflation reflexly depress cardiovascular function in a dog model?
Expansion of the lung can reflexly depress heart rate, ventricular contractility, systemic vasomotor tone, and cardiac output independent of direct mechanical influences.
Ashton et al. (1985) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: