Key result
A high neutrophil-to-lymphocyte ratio was an independent risk factor for high carotid artery intima-media thickness in patients with type 2 diabetes (OR 140.89; 95% CI 1.71-11615.30; P=0.028).
Why the study?
Is high neutrophil-to-lymphocyte ratio associated with increased carotid artery intima-media thickness in patients with type 2 diabetes?
Case-Control (n=570)
Is high neutrophil-to-lymphocyte ratio associated with increased carotid artery intima-media thickness in patients with type 2 diabetes?
Odds Ratio: 140.89 (95% CI 1.71–11615.3)
p-value: p=0.028
High neutrophil-to-lymphocyte ratio is independently associated with increased carotid intima-media thickness in patients with type 2 diabetes, suggesting its potential as a biomarker for subclinical atherosclerosis.
May support NLR as a subclinical atherosclerosis marker in type 2 diabetes; leaves open its incremental prognostic value in prospective cohorts.
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Li et al. (2016) conducted a case-control in Type 2 diabetes (n=570). High neutrophil-to-lymphocyte ratio (NLR) vs. Lower NLR was evaluated on High carotid artery intima-media thickness (cIMT) (OR 140.89, 95% CI 1.71-11615.30, p=0.028). A high neutrophil-to-lymphocyte ratio was an independent risk factor for high carotid artery intima-media thickness in patients with type 2 diabetes (OR 140.89; 95% CI 1.71-11615.30; P=0.028).
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