Key result
Intravenous magnesium sulfate significantly reduced the incidence of postoperative ventricular arrhythmias compared to control (5.0% vs 22.5%) in patients undergoing cardiac surgery.
Why the study?
Does postoperative intravenous magnesium sulphate reduce the incidence of ventricular arrhythmias in patients following cardiopulmonary bypass in open heart surgery?
Population
80 patients undergoing open heart surgery with cardiopulmonary bypass
Comparison
Magnesium Sulphate (intravenous, postoperative) vs No magnesium
Design
Cohort
Follow-up
ICU stay
Authors
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Magnesium was associated with fewer postoperative ventricular arrhythmias after bypass; hypothesis-generating and leaves open need for RCTs before practice change.
RCT (n=80)
Randomized
No
Does postoperative intravenous magnesium sulphate reduce the incidence of ventricular arrhythmias in patients following cardiopulmonary bypass in open heart surgery?
Absolute Event Rate: 5% vs 22.5%
p-value: p=0.023
Routine intravenous magnesium administration after cardiopulmonary bypass reduces the incidence of postoperative ventricular arrhythmias.
Karim et al. (2018) conducted an RCT in Cardiac surgery under cardiopulmonary bypass (n=80). Magnesium Sulphate vs. Conventional treatment (no magnesium) was evaluated on Incidence of ventricular arrhythmias (p=0.023). Intravenous magnesium sulfate significantly reduced the incidence of postoperative ventricular arrhythmias compared to control (5.0% vs 22.5%) in patients undergoing cardiac surgery.
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