Why the study?
Does hydrous magnesium silicate (talc) powder induce cardio-pericardial adhesions in a canine model?
Population
40 dogs undergoing 46 operations
Design
Preclinical
Follow-up
up to 4 weeks
Authors
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Hypothesis-generating in canine models; leaves open translation to human pericardial applications.
Does hydrous magnesium silicate (talc) powder induce cardio-pericardial adhesions in a canine model?
Talc powder effectively induces localized cardio-pericardial adhesions and neovascularization in a canine model without fluid accumulation.
Samuel Thompson (1939) studied this question.
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