Why the study?
Is 24-h ambulatory blood pressure more closely related to impaired endothelium-dependent vasodilation than office blood pressure in untreated hypertensive patients?
Is 24-h ambulatory blood pressure more closely related to impaired endothelium-dependent vasodilation than office blood pressure in untreated hypertensive patients?
Ambulatory blood pressure is not superior to office blood pressure in correlating with endothelial dysfunction in hypertensive patients, possibly due to the impact of mental alertness on vasodilation.
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Office BP correlates similarly with endothelial dysfunction as 24-h ABP; leaves open whether ambulatory monitoring adds value and requires prospective validation.
Bengt von zur Mühlen (2000) studied this question.