Why the study?
Is long-term infusion of propofol safe and effective compared to midazolam for sedation of critically ill intubated patients?
Population
Critically ill intubated patients requiring long-term sedation (> 7 days)
Comparison
Propofol long-term infusion (> 7 days) vs Midazolam long-term infusion
Design
Review
Follow-up
> 7 days
Authors
Loading...
Hypertriglyceridemia monitoring required with propofol sedation; review leaves open prospective RCTs for confirmation.
Is long-term infusion of propofol safe and effective compared to midazolam for sedation of critically ill intubated patients?
Long-term infusion of propofol is a practical alternative to midazolam for sedation of intubated patients, though adverse effects like hypertriglyceridemia must be monitored.
Miller et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: