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August 1, 1986Journal of Applied Physiology

Baroreflex responsiveness is maintained during isometric exercise in humans

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Why the study?

Does isometric handgrip exercise alter carotid baroreflex control of arterial pressure and heart period in healthy young men?

Population

9 healthy young men

Comparison

Isometric handgrip exercise and anticipation of… vs Supine control

Design

Other

Authors

TEThomas J. EbertCross-Cutting Cardiology

Discussion

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Member takes

Overview

Suggests central resetting of baroreflex during isometric exercise; leaves open translation to patients with cardiovascular disease.

Structured PICO

Does isometric handgrip exercise alter carotid baroreflex control of arterial pressure and heart period in healthy young men?

P
Population
9 healthy young men
I
Intervention
Isometric handgrip exercise (20% of maximum voluntary contraction) and anticipation of exercise, with incremental intensities of neck suction and pressure to alter carotid sinus transmural pressure
C
Comparator
Supine control
O
Outcome
Changes in R-R interval and mean arterial pressure in response to carotid stimuli (baroreflex sensitivity and function curves)surrogate

Isometric handgrip exercise shifts baroreflex function curves rightward without changing baroreflex sensitivity, suggesting central neural influences alter baroreflex function.

Cite This Study

Thomas J. Ebert (1986) studied this question.

synapsesocial.com/papers/6a992c4a7384e28de71ff8abhttps://doi.org/10.1152/jappl.1986.61.2.797
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lack of Effect of Isometric Handgrip Exercise on the Responses of the Carotid Sinus Baroreceptor Reflex in Man1978 · 48 citations
  2. 2Effects of isometric exercise on the carotid baroreflex in hypertensive subjects.1982 · 15 citations
  3. 3Effect of Isometric Hand-Grip Exercise on the Carotid Sinus Baroreceptor Reflex in Man1978 · 77 citations
  4. 4Carotid baroreceptor reflex regulation of forearm vascular resistance in man.1983 · 29 citations
  5. 5Exercise intensity influences cardiac baroreflex function at the onset of isometric exercise in humans2007 · 37 citations