What does this research mean for the field?

Exposure to various environmental pollutants is linked to adverse mental, neurodevelopmental, reproductive, and pregnancy outcomes through interrelated pathways such as oxidative stress, neuroinflammation, and endocrine disruption. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To summarize current evidence on the effects of major environmental pollution sources on mental, neurodevelopmental, reproductive, and pregnancy outcomes, along with their underlying biological mechanisms.

September 3, 2026Journal of Psychosexual HealthOpen Access

Environmental Pollution Exposure and Its Impact on Mental and Reproductive Health: A Review

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Authors

ASAbhinav Sahay ASArundhati Sharma UMUpanshu Mishra

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Overview

Narrative review reveals environmental contaminant exposure harms mental, neurodevelopmental, and reproductive outcomes across populations, highlighting urgent needs for regulatory policy.

Key Points

To summarize current evidence on the effects of major environmental pollution sources on mental, neurodevelopmental, reproductive, and pregnancy outcomes, along with their underlying biological mechanisms.
Conducted a narrative review of peer-reviewed literature evaluating exposures to air pollutants, endocrine disruptors (bisphenols, phthalates), heavy metals (lead, mercury, cadmium), pesticides, PFAS, polychlorinated biphenyls, dioxins, and microplastics.
Synthesized mechanistic pathways using a lifelong exposome approach.
Pollutant exposures are consistently linked to depression, anxiety, cognitive dysfunction, neurodevelopmental abnormalities, decreased semen quality, reduced fecundability, ovarian dysfunction, abnormal sexual maturation, placental damage, and fetal developmental defects.
Pathophysiological mechanisms are driven by oxidative stress, neuroinflammation, endocrine disruption, mitochondrial dysfunction, immune dysregulation, vascular injury, and epigenetic modifications.
Combined pollutant exposures display potential additive or synergistic toxic effects, disproportionately impacting vulnerable groups such as pregnant women, infants, children, and socioeconomically disadvantaged populations.

Cite This Study

Sahay et al. (2026) studied this question.

synapsesocial.com/papers/6a993511636c6408cfa7ce62 https://doi.org/10.1177/26318318261479134

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September 3, 2026Journal of Psychosexual HealthOpen Access

Environmental Pollution Exposure and Its Impact on Mental and Reproductive Health: A Review

View Full Paper

Ask AI

Bookmark

Authors

ASAbhinav Sahay ASArundhati Sharma UMUpanshu Mishra

Discussion

Member takes

Overview

Narrative review reveals environmental contaminant exposure harms mental, neurodevelopmental, and reproductive outcomes across populations, highlighting urgent needs for regulatory policy.

Key Points

To summarize current evidence on the effects of major environmental pollution sources on mental, neurodevelopmental, reproductive, and pregnancy outcomes, along with their underlying biological mechanisms.
Conducted a narrative review of peer-reviewed literature evaluating exposures to air pollutants, endocrine disruptors (bisphenols, phthalates), heavy metals (lead, mercury, cadmium), pesticides, PFAS, polychlorinated biphenyls, dioxins, and microplastics.
Synthesized mechanistic pathways using a lifelong exposome approach.
Pollutant exposures are consistently linked to depression, anxiety, cognitive dysfunction, neurodevelopmental abnormalities, decreased semen quality, reduced fecundability, ovarian dysfunction, abnormal sexual maturation, placental damage, and fetal developmental defects.
Pathophysiological mechanisms are driven by oxidative stress, neuroinflammation, endocrine disruption, mitochondrial dysfunction, immune dysregulation, vascular injury, and epigenetic modifications.
Combined pollutant exposures display potential additive or synergistic toxic effects, disproportionately impacting vulnerable groups such as pregnant women, infants, children, and socioeconomically disadvantaged populations.

Cite This Study

Sahay et al. (2026) studied this question.

synapsesocial.com/papers/6a993511636c6408cfa7ce62 https://doi.org/10.1177/26318318261479134

View Full Paper

Ask AI

Bookmark