Key result
In newborn dogs, the sympathetic nervous system becomes functional before peripheral sympathetic fibers reach full maturity at 2 months of age.
Population
Newborn dogs (studied from birth to 56 days of age)
Comparison
Observation of development; bilateral adrenal… vs Different developmental stages
Design
Preclinical
Follow-up
up to 56 days of age
Authors
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Hypothesis-generating for neonatal autonomic maturation; leaves open human translation and clinical relevance.
In newborn dogs, the sympathetic nervous system is functionally capable of regulating cardiovascular responses before sympathetic nerve fibers are fully mature.
Gauthier et al. (1975) studied Development of sympathetic innervation. Postnatal development was evaluated on Sympathetic nervous system functionality and norepinephrine content. In newborn dogs, the sympathetic nervous system becomes functional before peripheral sympathetic fibers reach full maturity at 2 months of age.
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