Population
Fetal, neonatal, and mature canine hearts
Design
Preclinical
Authors
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Challenges prior canine sympathetic timelines; extends developmental models but leaves open human perinatal translation.
Sympathetic nerve processes appear in the developing canine heart earlier than previously recognized, aligning with progressive neonatal development of sympathetic electrophysiologic effects.
Ursell et al. (1990) studied this question.
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