Why the study?
Does pulmonary vascular sensitivity and responsiveness to inhaled nitric oxide change during newborn development in lambs?
Does pulmonary vascular sensitivity and responsiveness to inhaled nitric oxide change during newborn development in lambs?
Pulmonary vascular responsiveness and sensitivity to inhaled nitric oxide decrease with age in newborn lambs, independent of changes in guanylate cyclase activity.
No takes yet. Share an insight, caveat, or question.
Neonatal iNO use in humans should remain unchanged; leaves open age-dependent mechanisms beyond guanylate cyclase for future study.
Powel et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: