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November 5, 2020Open Access

Carotid Intima-Media Thickness and Presence or Absence of Plaque Improves Prediction of Coronary Heart Disease Risk. The ARIC (Atherosclerosis Risk In Communities) Study

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Key result

Carotid intima-media thickness and the presence or absence of plaque improve coronary heart disease risk prediction when added to traditional risk factors.

Why the study?

Does adding carotid intima-media thickness (C-IMT) and the presence or absence of plaque to traditional risk factors improve coronary heart disease (CHD) risk prediction?

Population

Participants in the ARIC (Atherosclerosis Risk In Communities) Study

Comparison

Carotid intima-media thickness and the presence… vs Traditional risk factors (TRF) alone

Design

Cohort

Authors

Eric Boerwinkle
Eric BoerwinklePreventive Cardiology
LCLloyd E. ChamblessPreventive CardiologyVNVijay NambiGeneral / Preventive / Lipids

Discussion

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Member takes

Overview

This study evaluates whether assessing carotid intima-media thickness and plaque provides incremental value over traditional risk factors for predicting coronary heart disease.

Structured PICO

Does adding carotid intima-media thickness (C-IMT) and the presence or absence of plaque to traditional risk factors improve coronary heart disease (CHD) risk prediction?

P
Population
Participants in the ARIC (Atherosclerosis Risk In Communities) Study
I
Intervention
Carotid intima-media thickness (C-IMT) and the presence or absence of plaque added to traditional risk factors (TRF)
C
Comparator
Traditional risk factors (TRF) alone
O
Outcome
Coronary heart disease (CHD) risk prediction

This study evaluates whether assessing carotid intima-media thickness and plaque provides incremental value over traditional risk factors for predicting coronary heart disease.

Cite This Study

Boerwinkle et al. (2020) studied this question. Carotid intima-media thickness and the presence or absence of plaque improve coronary heart disease risk prediction when added to traditional risk factors.

synapsesocial.com/papers/6a997807b01d932fdc7c97cdhttps://doi.org/10.17615/8pyz-rm95
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Common carotid artery intima-media thickness is as good as carotid intima-media thickness of all carotid artery segments in improving prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study2011 · 175 citations
  2. 2Carotid Intima–Media Thickness and Carotid Plaques Improves Prediction of Obstructive Angiographic Coronary Artery Disease in Women2012 · 27 citations
  3. 3Carotid Intima‐Media Thickness and the Risk of Sudden Cardiac Death: The ARIC Study and the CHS2020 · 22 citations
  4. 4Redefining the exact roles and importance of carotid intima-media thickness and carotid plaque thickness in predicting cardiovascular events2024 · 8 citations
  5. 5Mannheim Carotid Intima-Media Thickness and Plaque Consensus (2004–2006–2011)2012 · 1,833 citations