Key result
Polyurethane prostheses prototypes for cardiac valve replacement were developed and passed biocompatibility testing, showing good hemodynamic performance in experimental studies.
Population
In vitro models for the development of cardiac valve prostheses for patients with congenital heart disease
Design
Preclinical
Authors
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Should not alter clinical valve selection; leaves open translation of polyurethane prototypes to human trials.
Segmented polyurethane prostheses prototypes for right ventricular remodeling in congenital heart disease demonstrated acceptable biocompatibility and macroscopic appearance in initial in vitro testing.
MA Maluf (2013) studied Congenital heart disease and cardiac valve disease. Polyurethane prostheses (SPU) was evaluated on Biocompatibility, physical, hydrodynamic, and durability tests. Polyurethane prostheses prototypes for cardiac valve replacement were developed and passed biocompatibility testing, showing good hemodynamic performance in experimental studies.
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