Key result
Intravenous barbiturate (n=28) and N2O-O2-halothane (n=12) induction resulted in equal elevations of pulmonary pressures, while systemic blood pressure increased more with barbiturates.
Why the study?
Does intravenous barbiturate compared to inhalation of N2O-O2-halothane affect pulmonary hemodynamics and acid-base balance during induction of anesthesia?
Observational (n=40)
Does intravenous barbiturate compared to inhalation of N2O-O2-halothane affect pulmonary hemodynamics and acid-base balance during induction of anesthesia?
Induction of anesthesia with either intravenous barbiturate or inhaled N2O-O2-halothane causes equal elevations in pulmonary pressures, which may increase cardiac strain in vulnerable patients.
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Both regimens may raise pulmonary pressures and RV strain in vulnerable patients; hypothesis-generating for induction choice in pulmonary hypertension.
Sørensen et al. (1977) conducted an observational in Induction of anesthesia (n=40). Intravenous administration of barbiturate vs. Inhalation of N2O-O2-halothane was evaluated on Changes in pulmonary hemodynamics and acid-base balance. Intravenous barbiturate (n=28) and N2O-O2-halothane (n=12) induction resulted in equal elevations of pulmonary pressures, while systemic blood pressure increased more with barbiturates.
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