Key result
An aortic height index >2.44 cm/m was associated with a greater ascending aorta expansive rate after aortic valve replacement compared to an index ≤2.44 cm/m (0.81 vs 0.14 mm/year; P=0.009).
Why the study?
To describe the natural history of the ascending aorta in elderly patients after AVR for aortic valve stenosis and clarify risk factors associated with ascending aorta progression.
Does a pre-operative aortic height index > 2.44 cm/m predict a greater rate of ascending aorta dilatation in elderly patients after aortic valve replacement for severe aortic stenosis?
Population
87 elderly patients after AVR for severe aortic valve stenosis in Fuwai Hospital
Comparison
Pre-AVR AHI > 2.44 cm/m vs AHI ≤ 2.44 cm/m
Design
Retrospective review
Follow-up
Mean 4.0 ± 1.3 years
Authors
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May support closer post-AVR aortic surveillance; leaves open whether thresholds should guide decisions in prospective studies.
Cohort (n=87)
No
Does a pre-operative aortic height index > 2.44 cm/m predict a greater rate of ascending aorta dilatation in elderly patients after aortic valve replacement for severe aortic stenosis?
Absolute Event Rate: 0.81% vs 0.14%
p-value: p=0.009
In elderly patients undergoing AVR for severe aortic stenosis, a pre-operative aortic height index > 2.44 cm/m is a significant risk factor for progressive ascending aortic dilatation.
Gong et al. (2022) conducted a cohort in Severe aortic valve stenosis (n=87). Aortic height index (AHI) > 2.44 cm/m vs. Aortic height index (AHI) ≤ 2.44 cm/m was evaluated on Ascending aorta diameter expansive rate (p=0.009). An aortic height index >2.44 cm/m was associated with a greater ascending aorta expansive rate after aortic valve replacement compared to an index ≤2.44 cm/m (0.81 vs 0.14 mm/year; P=0.009).
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