Key result
Human parechovirus encephalitis in infants was associated with neurodevelopmental sequelae in 62.5% (5 of 8) of cases at 12 months, despite reassuring short-term outcomes at discharge.
Population
13 infants with suspected encephalitis and human parechovirus infection identified prospectively in 5…
Design
Cohort
Follow-up
12 months after discharge
Authors
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May warrant extended neurodevelopmental surveillance despite reassuring discharge; leaves open optimal strategies pending larger studies.
Observational (n=9)
Yes
Human parechovirus encephalitis in infants is associated with significant neurodevelopmental sequelae at 12 months despite reassuring short-term outcomes.
Britton et al. (2016) conducted an observational in Human parechovirus (HPeV) encephalitis (n=9). Human parechovirus (HPeV) encephalitis was evaluated on Neurodevelopmental sequelae at 12 months assessed by the Ages and Stages Questionnaire (ASQ). Human parechovirus encephalitis in infants was associated with neurodevelopmental sequelae in 62.5% (5 of 8) of cases at 12 months, despite reassuring short-term outcomes at discharge.
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