Key result
Hospitalized HPeV infection linked to significant developmental delay in ~19% of infants at 12 months.
Why the study?
The human parechovirus is an increasingly recognised cause of sepsis and CNS infection in young infants with limited long-term outcome data.
What are the neurodevelopmental outcomes and quality of life in infants at 12 months following hospitalised human parechovirus infection?
Cohort (n=46)
Yes
What are the neurodevelopmental outcomes and quality of life in infants at 12 months following hospitalised human parechovirus infection?
A high proportion of infants hospitalised with human parechovirus infection show developmental concerns at 12 months, suggesting a need for careful long-term follow-up.
No takes yet. Share an insight, caveat, or question.
May warrant developmental surveillance after infant HPeV hospitalization; hypothesis-generating and requires prospective confirmation before practice change.
Britton et al. (2017) conducted a cohort in Human parechovirus (HPeV) infection (n=46). Hospitalised human parechovirus (HPeV) infection was evaluated on Significant concern in developmental attainment (ASQ3 score <2 standard deviation below population mean). At 12-month follow-up after hospitalised HPeV infection, 19% of infants showed significant concern in developmental attainment and 50% showed some concern.
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