Key result
Pulsatile flow cardiopulmonary bypass significantly reduced the incidence of acute kidney injury compared to non-pulsatile flow (10% vs 33.3%, p<0.05) in elderly patients undergoing CABG.
Why the study?
Does pulsatile flow cardiopulmonary bypass improve renal function and reduce acute kidney injury in elderly patients undergoing CABG?
Population
41 patients aged above 70 years undergoing elective on-pump coronary artery bypass grafting. Exclusion…
Comparison
Pulsatile flow cardiopulmonary bypass. vs Non-pulsatile flow cardiopulmonary bypass.
Design
RCT, randomly divided into two groups
Follow-up
3 days postoperative
Authors
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Supports pulsatile flow CPB in elderly CABG to reduce AKI; extends randomized evidence for perfusion strategy selection.
RCT (n=41)
Randomized
No
Does pulsatile flow cardiopulmonary bypass improve renal function and reduce acute kidney injury in elderly patients undergoing CABG?
Absolute Event Rate: 10% vs 33.3%
p-value: p=<0.05
Pulsatile flow cardiopulmonary bypass significantly preserves renal function and reduces the incidence of acute kidney injury compared to non-pulsatile flow in elderly patients undergoing CABG.
Faruk Hökenek (2013) conducted an RCT in Coronary artery disease requiring CABG (n=41). Pulsatile flow cardiopulmonary bypass vs. Non-pulsatile flow cardiopulmonary bypass was evaluated on Incidence of acute kidney injury (AKI) (p=<0.05). Pulsatile flow cardiopulmonary bypass significantly reduced the incidence of acute kidney injury compared to non-pulsatile flow (10% vs 33.3%, p<0.05) in elderly patients undergoing CABG.
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