Key result
Intravenous etomidate provided significantly better control of heart rate, systolic, diastolic, and mean arterial blood pressure during induction and intubation compared to propofol in controlled hypertensive patients.
Why the study?
The study was conducted to compare the hemodynamic effects of etomidate and propofol when used as induction agents in controlled hypertensive patients undergoing surgery under general anesthesia.
Does etomidate improve hemodynamic stability compared to propofol in controlled hypertensive patients during induction of general anesthesia?
RCT (n=60)
Double-blind
Computer-generated randomized method
No
Does etomidate improve hemodynamic stability compared to propofol in controlled hypertensive patients during induction of general anesthesia?
p-value: p=<0.05
Supports preferring etomidate over propofol for induction in controlled hypertensives; confirms hemodynamic advantages in this RCT.
Aim: To study and compare the hemodynamic effects of etomidate and propofol when used in controlled hypertensive patients as an induction agent. Materials and methods: It is a prospective randomized double-blind comparative study. After Institutional Ethics Committee approval, 60 patients with controlled hypertension undergoing surgery under general anesthesia and willing to participate in the study were included, i.e., the patients fulfilling the inclusion criteria were included.
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Shubha Bhat (2021) conducted an RCT in Controlled hypertension undergoing surgery under general anesthesia (n=60). Etomidate vs. Propofol 2 mg/kg IV was evaluated on Hemodynamic stability (Heart rate, SBP, DBP, MAP) during induction and intubation (p=<0.05). Intravenous etomidate provided significantly better control of heart rate, systolic, diastolic, and mean arterial blood pressure during induction and intubation compared to propofol in controlled hypertensive patients.
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