Key result
Mechanical prophylaxis with elastic compression and intermittent pneumatic compression can further reduce DVT/PE incidence beyond the 50% reduction estimated for pharmacological prophylaxis.
Why the study?
Does mechanical and pharmacological thromboprophylaxis reduce the incidence of DVT and PE in hospitalized patients?
Does mechanical and pharmacological thromboprophylaxis reduce the incidence of DVT and PE in hospitalized patients?
Mechanical and pharmacological thromboprophylaxis are advocated to reduce the high incidence of venous thromboembolism in at-risk hospitalized patients.
May support combined prophylaxis in hospitalized patients; hypothesis-generating and requires randomized confirmation before practice change.
Venous thromboembolism (VT) has always attracted the attention of the scientific community as one of the most common causes of acquired morbidity and mortality in hospitalized patients. The objective of VT prophylaxis protocols is mostly aimed at preventing deep vein thrombosis (DVT) and pulmonary embolisms (PE). Their incidence may in fact be as high as 20% to 40% in high-risk populations, such as polytraumatized and critically ill patients (1). Although low-dose subcutaneous unfractionated heparin (UFH) or low molecular-weight heparin (LMWH) are estimated to reduce VT incidence by 50% (2), several studies (3-5) have demonstrated that mechanical prophylaxis with elastic compression and intermittent pneumatic compression (IPC) can further reduce the incidence of DVT/PE, and are widely advocated in at risk patients.
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Ganau et al. (2019) conducted a review in Venous thromboembolism. Mechanical and pharmacological thromboprophylaxis was evaluated. Mechanical prophylaxis with elastic compression and intermittent pneumatic compression can further reduce DVT/PE incidence beyond the 50% reduction estimated for pharmacological prophylaxis.
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