Key result
Takotsubo syndrome is an increasingly recognized but challenging to diagnose clinical entity characterized by reversible acute myocardial dysfunction often triggered by stress.
Why the study?
Diagnosis of Takotsubo syndrome is often challenging due to nonspecific clinical presentation and inconclusive noninvasive diagnostic imaging, leading to frequent underdiagnosis or misdiagnosis.
This review highlights the clinical presentation, diagnostic work-up, and management of Takotsubo syndrome, emphasizing the challenges in its diagnosis.
Diagnostic challenges in Takotsubo syndrome warrant careful evaluation; leaves open refinement of criteria via prospective studies.
PURPOSE OF REVIEW: Takotsubo syndrome represents an increasingly recognized clinical entity characterized by a reversible acute myocardial dysfunction, often triggered by an emotional or physical stress, and independent of an underlying epicardial coronary artery disease. The diagnosis is often challenging because of the nonspecific clinical presentation and the inconclusive noninvasive diagnostic imaging. RECENT FINDINGS: The present review provides a brief overview of Takotsubo syndrome clinical presentation and guides the clinician through the diagnostic work-up of Takotsubo syndrome, highlighting clues into differential diagnosis. A review of clinical management is also provided. SUMMARY: Despite increasing awareness and recognition, the diagnosis of Takotsubo syndrome remains challenging and Takotsubo syndrome is often underdiagnosed or misdiagnosed. The prompt recognition of Takotsubo syndrome portends relevant prognostic and therapeutic implications.
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Buono et al. (2019) conducted a review in Takotsubo syndrome. Takotsubo syndrome is an increasingly recognized but challenging to diagnose clinical entity characterized by reversible acute myocardial dysfunction often triggered by stress.
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