Key result
Brr2p interacts with multiple splicing factors including Prp8p and Prp16p, suggesting it plays a central role in mediating protein recruitment and RNA rearrangements in the yeast spliceosome.
Population
Saccharomyces cerevisiae (yeast) spliceosome proteins
Design
Preclinical
Authors
Loading...
Should not yet change practice; leaves open Brr2p homolog roles in human cardiac splicing disorders.
Brr2p interacts with multiple splicing factors, suggesting a central role in regulating the order of events in the spliceosome complex.
Nues et al. (2001) studied Saccharomyces cerevisiae spliceosome function. Brr2p protein interactions was evaluated. Brr2p interacts with multiple splicing factors including Prp8p and Prp16p, suggesting it plays a central role in mediating protein recruitment and RNA rearrangements in the yeast spliceosome.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: