Key result
Increased plasma platelet-activating factor levels (1-20 ng/mL) were detected in patients with culture-positive septicemia and anaphylactoid reactions, supporting its role in these disease states.
Why the study?
Are increased levels of platelet-activating factor (PAF) detectable in plasma from patients with septicemia and other diseases?
Population
Patients with septicemia, adverse anaphylactoidic reaction, allergic asthma, idiopathic thrombocytopenic…
Design
Case_series
Authors
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PAF elevation in septicemia is hypothesis-generating; prospective trials needed before any clinical role.
Observational
Are increased levels of platelet-activating factor (PAF) detectable in plasma from patients with septicemia and other diseases?
Increased plasma PAF levels are detectable in patients with septicemia and anaphylactoid reactions, supporting a role for PAF in these disease states.
Heuer et al. (1991) conducted an observational in Septicemia and other diseases. Septicemia and other inflammatory conditions vs. Normal physiological state (PAF <0.5 ng/mL) was evaluated on Plasma platelet-activating factor (PAF) levels. Increased plasma platelet-activating factor levels (1-20 ng/mL) were detected in patients with culture-positive septicemia and anaphylactoid reactions, supporting its role in these disease states.
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