Key result
Direct measurement of renal artery pressure using a glass micropipette yielded an average of 103.8 mmHg compared to 107.2 mmHg from a femoral artery catheter (P<0.05), without altering renal blood flow.
Population
13 Sprague-Dawley rats
Comparison
Direct measurement of renal artery pressure… vs Femoral artery catheter and contralateral right…
Design
Preclinical
Authors
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Micropipette renal pressure measurement is feasible in rats without flow disruption; leaves open translation to clinical hypertension research.
Absolute Event Rate: 103.8% vs 107.2%
p-value: p=<0.05
A glass micropipette fitted to a low displacement pressure transducer provides an accurate method for direct measurement of renal artery pressure in rats without altering renal blood flow.
Murphy et al. (1982) studied this question. Direct measurement of renal artery pressure using a glass micropipette vs. Femoral artery catheter was evaluated on Renal artery pressure compared to mean arterial pressure (p=<0.05). Direct measurement of renal artery pressure using a glass micropipette yielded an average of 103.8 mmHg compared to 107.2 mmHg from a femoral artery catheter (P<0.05), without altering renal blood flow.
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