Key result
Global longitudinal strain measured by 3D geometric modelling from cine CMR demonstrated good absolute agreement with 2D speckle tracking echocardiography (ICC 0.820; 95% CI 0.720-0.885).
Why the study?
Calculation of strain via 3D geometric modelling enables deformation analyses independent of 2D image plane constraints, prompting comparison with conventional 2D-STE.
Does longitudinal strain measurement by 3D modelling from cine CMR provide comparable values to 2D speckle tracking echocardiography in healthy individuals and patients with cardiac disease?
Population
80 prospectively recruited participants (48 healthy controls, 30 non-ischaemic cardiac disease, 2 heart transplant recipients)
Comparison
Geometric 3D analysis of cine CMR vs conventional 2D-STE
Design
Prospective comparative study
Authors
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Supports GLS comparability in research cohorts; leaves open clinical substitution for 2D echocardiography pending outcome validation.
Observational (n=80)
Does longitudinal strain measurement by 3D modelling from cine CMR provide comparable values to 2D speckle tracking echocardiography in healthy individuals and patients with cardiac disease?
Effect estimate: ICC 0.820 (95% CI 0.720-0.885)
Fully automated calculation of LV GLS from geometric 3D CMR analysis is feasible and shows good agreement with conventional 2D-STE, potentially enhancing the diagnostic value of routine cine CMR for LV systolic function assessment.
Zhao et al. (2021) conducted an observational in Healthy controls and non-ischaemic cardiac disease (n=80). 3D geometric modelling from cine CMR vs. 2D speckle tracking echocardiography (2D-STE) was evaluated on Absolute agreement of average global longitudinal strain (GLS) (ICC 0.820, 95% CI 0.720-0.885). Global longitudinal strain measured by 3D geometric modelling from cine CMR demonstrated good absolute agreement with 2D speckle tracking echocardiography (ICC 0.820; 95% CI 0.720-0.885).
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