Key result
Indium-111-labeled platelet imaging, but not leukocyte imaging, is a sensitive technique for detecting experimental infective endocarditis.
Why the study?
Does imaging with 111In-labeled platelets or leukocytes detect experimental infective endocarditis in a rabbit model?
Does imaging with 111In-labeled platelets or leukocytes detect experimental infective endocarditis in a rabbit model?
Indium-111 labeled platelet imaging is a sensitive technique for detecting experimental infective endocarditis in a rabbit model, whereas leukocyte imaging is not.
No takes yet. Share an insight, caveat, or question.
Hypothesis-generating for 111In-platelet imaging in endocarditis; human studies needed before any clinical consideration.
Riba et al. (1979) studied experimental aortic valve infective endocarditis (n=29). indium-111 (111In)-labeled platelets vs. 111In-polymorphonuclear leukocytes and noncellular 111In was evaluated on abnormal 111In uptake in the region of the aortic valve. Indium-111-labeled platelet imaging, but not leukocyte imaging, is a sensitive technique for detecting experimental infective endocarditis.
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