Why the study?
Does scintigraphic imaging using autologous 111In-labelled platelets allow visualization of haemostatic and thromboembolic processes?
Does scintigraphic imaging using autologous 111In-labelled platelets allow visualization of haemostatic and thromboembolic processes?
Scintigraphic imaging with 111In-labelled platelets is a feasible method for visualizing various haemostatic and thromboembolic processes in vivo, with potentially increased sensitivity if investigated 4-5 days post-injection.
May support thrombus localization in select cases; leaves open its role in routine cardiovascular care.
Five cases of scintigraphic imaging of haemostatic and thromboembolic processes after injection of autologous 111In-labelled platelets are presented. The site of a liver puncture, atherosclerotic plaques in the abdominal aorta, deep vein thrombi, pulmonary embolism and the tip of an indwelling venous catheter could be visualized. Activity measurements corresponding to atherosclerotic plaques suggest that an increased sensitivity of this method may be achieved by extending the investigation period to 4-5 days after injection of 111In platelets.
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Schmidt et al. (1984) studied this question.
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