Key result
Scintigraphy with 111In-labeled autologous platelets detected venous thrombi in 86% of patients with confirmed deep venous thrombosis, though heparin may inhibit adherence to pulmonary emboli.
Why the study?
Does scintigraphy with 111In-labeled autologous platelets detect thrombi in patients with suspected venous thromboembolism?
Population
20 patients with suspected venous thrombosis and/or pulmonary embolism
Design
Case_series
Authors
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Should not yet change VTE imaging practice; hypothesis-generating for 111In-platelet scintigraphy in DVT.
Observational (n=20)
Does scintigraphy with 111In-labeled autologous platelets detect thrombi in patients with suspected venous thromboembolism?
Scintigraphy with 111In-labeled platelets is a promising noninvasive technique for detecting deep venous thrombosis, though concurrent heparin therapy may inhibit platelet adherence to pulmonary emboli.
Davis et al. (1980) conducted an observational in Suspected venous thrombosis and/or pulmonary embolism (n=20). Scintigraphy with 111In-labeled autologous platelets was evaluated on Accumulation of labeled platelets in venous thrombi among patients with positive findings on impedance plethysmography or contrast venography. Scintigraphy with 111In-labeled autologous platelets detected venous thrombi in 86% of patients with confirmed deep venous thrombosis, though heparin may inhibit adherence to pulmonary emboli.
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