Associations of low-density lipoprotein cholesterol and hemoglobin A1C with cardiovascular events and mortality in breast and prostate cancer patients

Figures

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  Fig. 1. The association of major cardiovascular events, all-cause mortality, and cancer recurrence with serum low-density protein cholesterol and hemoglobulin A1C in patients with breast or prostate cancers: analysis from Taipei Medical University Clinical Research Database. Hazards ratios with 95 % confidence intervals were used to express the association of major cardiovascular events, all-cause mortality, and cancer recurrence with different levels of serum low-density protein cholesterol and hemoglobulin A1C. The multivariable Cox proportional hazard model with time-dependent covariates was used. Red lines indicate breast cancer. Blue lines indicate prostate cancer. HbA1C = hemoglobulin A1C; LDL = low-density protein cholesterol; TMU CRD = Taipei Medical University Clinical Research Database; Ref = reference. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

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  Fig. 2. Multivariable adjusted hazard ratios for major cardiovascular events, all-cause mortality, and cancer recurrence according to levels of low-density lipoprotein cholesterol and hemoglobulin A1C on a continuous scale. Hazards ratios (solid lines) with 95 % confidence intervals (dashed lines) were calculated by the multivariable Cox proportional hazard model with time-dependent covariates was used. Red lines indicate breast cancer. Blue lines indicate prostate cancer. Black dash lines are the reference line, indicating no association with a hazard ratio of 1.0. HbA1C = hemoglobulin A1C; LDL = low-density protein cholesterol. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

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  Fig. 3. The association of major cardiovascular events, all-cause mortality, and cancer recurrence with serum low-density protein cholesterol and hemoglobulin A1C in patients with breast or prostate cancers: analysis from the TriNetX research network. Hazards ratios with 95 % confidence intervals were used to express the association of major cardiovascular events, all-cause mortality, and cancer recurrence with different levels of serum low-density protein cholesterol and hemoglobulin A1C. The Cox proportional hazard model with propensity score matching was used. Red lines indicate breast cancer. Blue lines indicate prostate cancer. HbA1C = hemoglobulin A1C; LDL = low-density protein cholesterol; Ref = reference. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)