Key result
Intermittent intravenous inoculation with 5 different serotypes of group B coxsackieviruses in mice provoked pathological changes resembling human proliferative glomerulonephritis at 6-7 months of age.
Authors
Loading...
Hypothesis-generating for coxsackievirus role in glomerulonephritis; leaves open relevance to human disease.
Isome et al. (2008) studied Glomerulonephritis. Successive inoculation of five different serotypes of group B coxsackieviruses (CB1 to CB5) was evaluated on Mesangial proliferation and PAS-positive mesangial deposits. Intermittent intravenous inoculation with 5 different serotypes of group B coxsackieviruses in mice provoked pathological changes resembling human proliferative glomerulonephritis at 6-7 months of age.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: