A Prospective Clinical Study to Assess the Hemodynamic Changes and Safety of 0.5% Levobupivacaine Hyperbaric for Spinal Anaesthesia in Adult Patients

This is the authors' abstract. We don't add key points for this paper.

Background: This study evaluates the hemodynamic effects safety and block characteristics of 0.5% hyperbaric levobupivacaine for spinal anesthesia in adults undergoing infraumbilical surgeries. Materials and Methods: A prospective study was conducted with 75 ASA I-II patients aged 18-65 years. Each patient received 3.5 ml of 0.5% hyperbaric levobupivacaine at the L2/L3 or L3/L4 level. Hemodynamic parameters were monitored, and sensory and motor block characteristics were assessed. Postoperative pain was recorded using the Visual Analog Scale (VAS). Results: Hemodynamic stability was observed, with 2.66% of patients experiencing hypotension and none reporting bradycardia. Sensory block onset averaged 2.37 ± 0.70 min, lasting 201.35 ± 16.50 min. Motor block onset was 4.57 ± 0.54 min, lasting 171.27 ± 7.57 min. Severe pain (VAS ≥4) occurred in 62.6% at 4 hours and 38.6% at 8 hours. Conclusions: Hyperbaric 0.5% levobupivacaine provides effective anesthesia with stable hemodynamics. However, shorter analgesia duration suggests a need for additional postoperative pain management.