Key result
There was a significant positive correlation between the increase in plasma noradrenaline level and the increase in brachial-ankle pulse wave velocity during a 200 µg/hr noradrenaline load (p=0.0020).
Why the study?
Does noradrenaline load during ECUM without ultrafiltration help evaluate arterial stiffness via pulse wave velocity in hemodialysis patients?
Observational (n=21)
No
Does noradrenaline load during ECUM without ultrafiltration help evaluate arterial stiffness via pulse wave velocity in hemodialysis patients?
Measuring the increase in pulse wave velocity during a 200 μg/hr noradrenaline load under ECUM without ultrafiltration may be a sensitive method to detect arterial stiffness in hemodialysis patients.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for noradrenaline-loaded PWV in assessing arterial stiffness in hemodialysis; prospective validation needed before clinical adoption.
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Shiota et al. (2004) conducted an observational in Hemodialysis (n=21). Noradrenaline load vs. Before noradrenaline load was evaluated on Correlation between the increase in plasma noradrenaline level and the increase in brachial-ankle pulse wave velocity (baPWV) during 200 µg/hr noradrenaline load (p=0.0020). There was a significant positive correlation between the increase in plasma noradrenaline level and the increase in brachial-ankle pulse wave velocity during a 200 µg/hr noradrenaline load (p=0.0020).
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