Key result
Prophylactic intravenous ephedrine infusion was more effective than fluid preload in preventing hypotension due to spinal anesthesia for lower abdominal and lower limb vascular surgery.
Why the study?
The study was conducted to evaluate the efficacy of ephedrine infusion without preblock crystalloid administration in reducing the incidence of hypotension during spinal anesthesia.
Does prophylactic intravenous ephedrine infusion prevent hypotension compared to fluid preload in patients undergoing lower abdominal and lower limb vascular surgery under spinal anesthesia?
Comparison
Volume preload vs ephedrine infusion without preblock crystalloid administration
Authors
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May warrant ephedrine infusion consideration in spinal anesthesia; leaves open confirmation in larger randomized trials.
RCT (n=50)
Does prophylactic intravenous ephedrine infusion prevent hypotension compared to fluid preload in patients undergoing lower abdominal and lower limb vascular surgery under spinal anesthesia?
Prophylactic intravenous ephedrine infusion is more effective than fluid preload for preventing hypotension during spinal anesthesia in lower abdominal and vascular surgery.
AshrafA H. Mahmoud Soliman (2021) conducted an RCT in Hypotension during spinal anesthesia (n=50). Ephedrine infusion vs. Volume preload was evaluated on Incidence of hypotension. Prophylactic intravenous ephedrine infusion was more effective than fluid preload in preventing hypotension due to spinal anesthesia for lower abdominal and lower limb vascular surgery.
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