Key result
Despite a blunted systolic blood pressure rise, overall vascular resistance and blood flow responses to epinephrine did not differ between healthy elderly and young subjects.
Why the study?
Does the vascular response to graded epinephrine infusion differ between healthy elderly and healthy young subjects?
Cross-Sectional (n=24)
Does the vascular response to graded epinephrine infusion differ between healthy elderly and healthy young subjects?
The balance between vascular alpha- and beta-adrenoceptors is preserved in healthy elderly individuals, challenging previous hypotheses of an age-related imbalance.
No takes yet. Share an insight, caveat, or question.
Supports preserved alpha-beta adrenoceptor balance in healthy aging; challenges prior imbalance hypotheses but should not yet change practice.
Klein et al. (1987) conducted a cross-sectional in Healthy (n=24). Elderly age vs. Young subjects was evaluated on Blood pressure response, vascular resistance, and calf blood flow. Despite a blunted systolic blood pressure rise, overall vascular resistance and blood flow responses to epinephrine did not differ between healthy elderly and young subjects.
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