Key result
Serum adiponectin levels were significantly lower in obese children compared to nonobese controls (3.63 vs 5.79 µg/mL, P<0.001) and were inversely associated with the presence of NAFLD.
Why the study?
Are serum adiponectin and resistin levels associated with non-alcoholic fatty liver disease in obese children?
Cross-Sectional (n=150)
No
Are serum adiponectin and resistin levels associated with non-alcoholic fatty liver disease in obese children?
Absolute Event Rate: 3.63% vs 5.79%
p-value: p=<0.001
Lower serum adiponectin levels are independently associated with the presence of non-alcoholic fatty liver disease in obese children, suggesting a potential protective role.
No takes yet. Share an insight, caveat, or question.
Lower adiponectin may mark NAFLD in obese children; cross-sectional data leave causal role and clinical utility open.
Zou et al. (2005) conducted a cross-sectional in Obesity and Non-alcoholic fatty liver disease (NAFLD) (n=150). Obesity vs. Nonobese controls was evaluated on Serum adiponectin levels (µg/mL) (p=<0.001). Serum adiponectin levels were significantly lower in obese children compared to nonobese controls (3.63 vs 5.79 µg/mL, P<0.001) and were inversely associated with the presence of NAFLD.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: