Key result
In patients with uncomplicated hypertension, left ventricular hypertrophy strongly predicted diastolic dysfunction severity, whereas inappropriate left ventricular mass showed only a modest correlation (r=0.201, p=0.025).
Why the study?
To evaluate the echocardiographic assessment of inappropriate left ventricular mass and left ventricular hypertrophy in patients with diastolic function.
Cross-Sectional (n=200)
No
Effect estimate: Correlation coefficient 0.201
p-value: p=0.025
In patients with simple hypertension, left ventricular hypertrophy and inappropriate left ventricular mass are associated with the severity of diastolic dysfunction.
Supports LV mass assessment for diastolic dysfunction severity in hypertension; hypothesis-generating and requires prospective validation before practice impact.
Objective: To evaluate the echo graphic assessment of inappropriate left ventricular mass and left ventricular hypertrophy in patients with diastolic function. Method: This cross sectional study was carried out at tertiary medical hospital where Two-dimensional echocardiography was performed on 200 patients with simple hypertension at a tertiary medical center. If a woman had an LVM index of more than 88 g/m2 of body-surface area, or if a man had an LVM index of more than 102 g/m2 of body-surface area, they were considered to have an unhealthy amount of LVM. Women with a septal wall thickness of more than 0/9 cm and males with a thickness of more than 1 cm are considered to have LVH. Early diastolic peak velocity (E) was compared to late diastolic peak velocity (A), deceleration time (DT), and early diastolic peak velocity (E′) were also assessed as echocardiographic parameters. Results: Patients' averaged systolic and diastolic blood pressure readings on the day of admission were 142.87 18.12 and 88.45 9.18 mmHg, respectively. Twenty-one percent of the individuals had an abnormal LV mass, with 5.6% having a mild abnormality and 5.6% having a severe abnormality. Patients with mild left ventricular hypertrophy had a higher mean age and body mass index (P 0.05). Patients with more severe ventricular hypertrophy had longer E/A ratios and longer deceleration times after controlling for age, gender, body mass index, and systolic and diastolic blood pressures. The mean body mass index (BMI) of subjects with severe was 33. 7 3.7 (P 0.001). Slightly different levels of diastolic dysfunction were associated with varying degrees of improper LV mass (P = 0.065). However, there was no correlation between E/A, E/E′, or deceleration time and excessive LV mass (P > 0.05). The relationship between diastolic dysfunction and LV mass was analyzed using Spearman's Rank test (P = 0.025). Conclusion: While LVH is a strong predictor of diastolic dysfunction severity as measured .......
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Md. Fazlul Karim (2022) conducted a cross-sectional in Simple hypertension (n=200). Left ventricular hypertrophy and inappropriate left ventricular mass vs. Normal left ventricular mass and geometry was evaluated on Association between the grade of diastolic dysfunction and the severity of inappropriate LV mass (Correlation coefficient 0.201, p=0.025). In patients with uncomplicated hypertension, left ventricular hypertrophy strongly predicted diastolic dysfunction severity, whereas inappropriate left ventricular mass showed only a modest correlation (r=0.201, p=0.025).
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