Key result
Inappropriate left ventricular mass index was associated with a 4.7-fold increased risk of myocardial infarction compared to appropriate LVMI in patients with essential hypertension.
Why the study?
Does inappropriate left ventricular mass index predict the risk of myocardial infarction, stroke, and persistent atrial fibrillation in patients with essential hypertension?
Cohort (n=968)
No
Does inappropriate left ventricular mass index predict the risk of myocardial infarction, stroke, and persistent atrial fibrillation in patients with essential hypertension?
Odds Ratio: 4.7
Absolute Event Rate: 16% vs 3.9%
p-value: p=0.03
A novel calculation for inappropriate left ventricular mass index correlates well with existing methods and predicts an increased risk of myocardial infarction in hypertensive patients, even in the absence of overt left ventricular hypertrophy.
Supports evaluation of inappropriate LVMI for MI risk stratification in hypertension without LVH; leaves open incremental value and needs prospective validation.
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S. E. Lozinsky (2017) conducted a cohort in Essential hypertension (n=968). Inappropriate left ventricular mass index (LVMI) vs. Appropriate LVMI was evaluated on Myocardial infarction (OR 4.70, p=0.03). Inappropriate left ventricular mass index was associated with a 4.7-fold increased risk of myocardial infarction compared to appropriate LVMI in patients with essential hypertension.
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